Dr. Thiele is Director of the Pediatric Epilepsy Program at Massachusetts General Hospital and Director, Herscot Center for Tuberous Sclerosis Complex (TSC) as well as Professor of Neurology, Harvard Medical School.

Dr. Thiele was instrumental in the founding of the Herscot Center, the first systematic and broad multi-disciplinary clinical program for longitudinal care for children and adults with TSC. Her research has focused on the effect of diet in pediatric epilepsy, particularly the use of low glycemic index treatment (LGIT) to keep blood sugar levels low and better manage childhood epilepsy.

Dr. Thiele graduated summa cum laude from Washington University in St. Louis, MO, with an A.B. in Biology and Religious Studies. She received her M.D. and Ph.D. in Neuroscience from Johns Hopkins University in Baltimore, MD. She is the author or co-author of nearly 200 peer-reviewed publications.